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Antidiabetic drugs as a class have been on the radar for the treatment of Alzheimers and dementia for quite a while, as appropriate insulin-signaling in the brain is essential for learning and memory, and insulin resistance may, therefore, lead to or worsen neurodegeneration
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The ECDTMD interface is relatively small with a buried solvent-accessible surface of 1015 2 , in contrast to a total of 1632 2 and 3278 2 in the peptide 5-GLP-1R and GLP-1-GLP-1R interfaces, respectively
Hypertension 65 (1), 101107
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